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品名： | Pierce Traut's Reagent (2-iminothiolane) |
产品简介:
规格
| Label Type: |
Conjugating Groups |
| Label or Dye: |
Sulfhydryl Group |
| Product Line: |
Pierce? |
| Solubility: |
DMF (Dimethylformamide), DMSO (Dimethylsulfoxide) |
| Spacer: |
Short |
| 化学反应性: |
Amine |
内容及储存
Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature
描述
Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 angstroms) terminated by a free sulfhydryl group.
Features of Thermo Scientific Pierce Traut's Reagent (2-iminothiolane):*
Simple—one-step conversion of amines to sulfhydryls
*
Specific—selective and spontaneous modification of primary amines at pH 7-10
* Preserves positive charge to maintain protein solubility
Traut's Reagent (2-iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition). Traut's Reagent reacts with primary amines (—NH2) to introduce sulfhydryl (—SH) groups while maintaining charge properties similar to the original amino group. Once added, sulfhydryl groups can be specifically targeted for reaction in a variety of useful labeling, crosslinking and immobilization procedures.
Flexible—incorporates a five-atom spacer arm to reduce steric hindrance
*
Soluble—preserves the original positive charge to preserve protein solubility
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For Research Use Only. Not for use in diagnostic procedures.
For Research Use Only. Not for use in diagnostic procedures.
